Paola Bertolazzi
Paola Bertolazzi Paola Bertolazzi
Research Associate

Tel.: +39 06 4993 7135
Fax: +39 06 4993 7137
email

Research interests

Algorithms, combinatorics and graph theory, bioinformatics, systems biology, computational biology.


Research groups

Selected publications
  • Fabio Previtali, Paola Bertolazzi, Giovanni Felici, Emanuel Weitschek: A novel method and software for automatically classifying Alzheimer's disease patients by magnetic resonance imaging analysis, Computer Methods and Programs in Biomedicine, http://www.cmpbjournal.com/article/S0169-2607(16)30775-1/fulltext, 2017
  • Paola Bertolazzi, Giovanni Felici, Festa P., Giulia Fiscon, Emanuel Weitschek: Integer programming models for feature selection: new extensions and a randomized solution algorithm, European Journal of Operational Research 250(2), 389-399, 2016
  • Cestarelli V, Giulia Fiscon, Giovanni Felici, Paola Bertolazzi, Emanuel Weitschek: CAMUR: Knowledge extraction from RNA-seq cancer data through equivalent classification rules, Bioinformatics 32 (5), 697-704, 2016
  • Giulia Fiscon, Emanuel Weitschek, Ciccozzi M., Paola Bertolazzi, Giovanni Felici: A novel feature selection method to extract multiple adjacent solutions for viral genomic sequences classification, BMC Bioinformatics, 2016
  • Arisi I., D'Onofrio M., Brandi R., Cattaneo A., Paola Bertolazzi, Fabio Cumbo, Giovanni Felici, Concettina Guerra: Time dynamics of protein complexes in the AD11 transgenic mouse model for Alzheimer's disease like pathology, Bmc Neuroscience, 2015
  • Paola Bertolazzi, Giovanni Felici, Festa P., Giulia Fiscon, Emanuel Weitschek: Integer Programming models for Feature Selection: new extensions and a randomized solution algorithm, European Journal of Operational Research, 2015
  • Paola Bertolazzi, Giovanni Felici, Giulia Fiscon, Emanuel Weitschek: Classifying DNA barcode multi-locus sequences with feature vectors and supervised approaches, Genome 58(5), 2015
  • Cestarelli V, Giulia Fiscon, Giovanni Felici, Paola Bertolazzi, Emanuel Weitschek: CAMUR: Knowledge extraction from RNA-seq cancer data through equivalent classification rules, Bioinformatics, 2015
  • Emanuel Weitschek, Giulia Fiscon, Paola Bertolazzi, Giovanni Felici: GELA: a software tool for the analysis of gene expression data., DEXA Workshops, 2015
  • Emanuel Weitschek, Giulia Fiscon, Cestarelli V, Cestarelli V, Paola Bertolazzi, Giovanni Felici: LAF Barcoding: classifying DNA Barcode multi-locus sequences with feature vectors and supervised approaches, Rovetta S., Angelini C., Bongcam-Rudloff E., Decarli A., Rancoita P.M.V. eds., 12th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, 2015
  • Emanuel Weitschek, Giulia Fiscon, Fustaino V, Giovanni Felici, Paola Bertolazzi: Clustering and Classification Techniques for Gene Expression Profiles Pattern Analysis, in: Pattern Recognition in Computational Molecular Biology: Techniques and Approaches, Elloumi M, Zomaya AY eds., Wiley Series in Bioinformatics, Wiley, 2015
  • Paola Bertolazzi, Bock M.E., Concettina Guerra, Paola Paci, Daniele Santoni: On the integration of protein-protein interaction networks with gene expression and 3D structural data: What can be gained?, European Physical Journal Plus, 129(6), 2014
  • Paola Bertolazzi, Concettina Guerra, Giampaolo Liuzzi: Predicting protein-ligand and protein-peptide interfaces, European Physical Journal Plus 129, 132-142, 2014
  • Cumbo F, Giovanni Felici, Paola Bertolazzi: Selecting relevant nodes and structures in biological networks. BiNAT: a new plugin for Cytoscape, F1000 3, 2014
  • Giulia Fiscon, Emanuel Weitschek, Paola Bertolazzi, De Cola M C, De Salvo S, Bramanti P, Giovanni Felici: EEG signals analysis to detect Alzheimer's disease patients, IASI-CNR, R. 14-10, 12/2014
  • Giulia Fiscon, Emanuel Weitschek, De Cola M C, De Salvo S, Bramanti P, Paola Bertolazzi, Giovanni Felici: EEG signals analysis to detect Alzheimer's disease patients, 2014
  • Giulia Fiscon, Emanuel Weitschek, Giovanni Felici, Paola Bertolazzi, De Salvo S, Bramanti P, De Cola M C: Alzheimer's disease patients classification through EEG signals processing, in the Proceedings of 2014 IEEE Symposium Series on Computational Intelligence, 2014 IEEE Symposium on Computational Intelligence and Data Mining (CIDM) Proceedings, 2014
  • Daniele Santoni, Swiercz A., Zmienko A, Kasprzak M, Blazewicz M, Paola Bertolazzi, Giovanni Felici: An integrated approach (CLuster Analysis Integration Method) to combine expression data and protein-protein interaction networks in agrigenomics: Application on Arabidopsis thaliana, OMICS, 18(2): 156-165, 2014
  • Emanuel Weitschek, Giulia Fiscon, Paola Bertolazzi, Festa P., Giovanni Felici: A new greedy randomized procedure for the feature selection problem, IV EURO WG Conference on Operational Research in Computational Biology, Bioinformatics and Medicine, 2014
  • Emanuel Weitschek, Giulia Fiscon, Giovanni Felici, Paola Bertolazzi: GELA: Gene Expression Logic Analyzer, Nettab2014 Workshop, From structural bioinformatics to integrative systems biology. Book of Abstract, 2014
  • Emanuel Weitschek, Giulia Fiscon, Fustaino V, Giovanni Felici, Paola Bertolazzi: Analysis of microarray and RNA-sequencing gene expression profiles through clustering and classification techniques, IASI-CNR, R. 14-11, 12/2014
  • Emanuel Weitschek, Daniele Santoni, Giulia Fiscon, De Cola M C, Paola Bertolazzi, Giovanni Felici: Next generation sequencing reads comparison with an alignment-free distance, BMC Research Notes, 7:869, 2014
  • Paola Bertolazzi, Bock M.E., Concettina Guerra: On the functional and structural characterization of hubs in protein-protein interaction networks, Biotechnology Advances 31, 274-286, 2013
  • Paola Bertolazzi, Bock M.E., Concettina Guerra, Paola Paci, Daniele Santoni: On the integration of protein-protein interaction networks with gene expression and 3d structural data: what can be gained?, IASI-CNR, R. 13-07, 2013
  • Emanuel Weitschek, Arisi I., Giovanni Felici, Paola Bertolazzi: Knowledge extraction in clinical data, IASI-CNR, R. 13-20, 12/2013
  • Emanuel Weitschek, Giovanni Felici, Paola Bertolazzi: Clinical data mining: problems, pitfalls and solutions, Wagner R.R., Tjoa A.M., Morvan F eds., DEXA - Database and Expert Systems Applications, 2013
  • Emanuel Weitschek, Giovanni Felici, Paola Bertolazzi: Microarray Logic Analyzer Software, IASI-CNR, R. 13-18, 12/2013
  • Emanuel Weitschek, Van Velzen R, Giovanni Felici, Paola Bertolazzi: BLOG 2.0: a software system for character-based species classification with DNA Barcode sequences. What it does, how to use it, Molecular Ecology Resources, 2013
  • Alberghina L., Gaglio D., Gelfi C., Moresco R.M., Mauri G., Paola Bertolazzi, Messa C., Gilardi M.C., Chiaradonna F., Vanoni M.: Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling, Frontiers in Physiology, 2012
  • Paola Bertolazzi, Concettina Guerra, Lampariello F., Giampaolo Liuzzi: Continuous global optimization for protein structure analysis, Il Nuovo Cimento 35C, 65-70, 2012
  • Emanuel Weitschek, Giovanni Felici, Paola Bertolazzi: MALA: A Microarray clustering and classification software, Wagner R.R., Tjoa A.M., Hameurlain A eds., DEXA - Database and Expert Systems Applications, 2012
  • Emanuel Weitschek, Lo Presti A., Drovandi G., Giovanni Felici, Ciccozzi M., Ciotti M., Paola Bertolazzi: Human polyomaviruses identification by logic mining techniques, BMC Virology Journal 9:58, 2012
  • Arisi I., D'Onofrio M., Brandi R, Felsani A, Capsoni S, Drovandi G., Giovanni Felici, Emanuel Weitschek, Paola Bertolazzi, Cattaneo A: Gene Expression Biomarkers in the Brain of a Mouse Model for Alzheimer's Disease: Mining of Microarray Data by Logic Classification and Feature Selection., Journal of Alzheimer's Disease 24, 2011
  • Paola Bertolazzi, Giovanni Felici: Nuova conoscenza vo' scavando, Sapere 5, 52-57, 2011
  • Busti S., Gotti, L., Balestrieri C., Querin L., Drovandi G., Giovanni Felici, Gabriella Mavelli, Paola Bertolazzi, Alberghina L., Vanoni M.: Overexpression of Far1, a cyclin-dependent kinase inhibitor, induces a large transcriptional reprogramming in which RNA synthesis senses Far1 in a Sfp1-mediated way, Biotechnology Advances, 2011
  • Paola Bertolazzi, Blazewicz J., Turkay M. eds.: Special Issue on Operations Research Models for Computational Biology, Bioinformatics and Medicine, Journal of Mathematical Models and Algorithms, 9, Springer, 2010
  • Paola Bertolazzi, Giovanni Felici, Festa P.: Logic Based Methods for SNPs Tagging and Reconstruction, Computers & Operations Research 37, 1419-1426, 2010
  • Paola Bertolazzi, Giovanni Felici, Lancia G.: Application of Feature Selection and Classification to Computational Molecular Biology, in: Biological data Mining, Chen J.K., Lonardi S. eds., 257-294, 2010
  • Paola Bertolazzi, Giovanni Felici, Emanuel Weitschek, Drovandi G., Lo Presti A., Ciccozzi M., Ciotti M.: Human Polyomaviruses genome analysis by logic mining techniques, IASI-CNR, R. 10-23, 12/2010
  • Paola Bertolazzi, Concettina Guerra, Giampaolo Liuzzi: A global optimization algorithm for protein surface alignment, BMC Bioinformatics 11, 488-498, 2010
  • Paola Bertolazzi, Giovanni Felici, Festa P.: Integer feature selection models and their solution, IASI-CNR, R. 09-18, 2009
  • Paola Bertolazzi, Giovanni Felici, Emanuel Weitschek: Learning to classify species with barcodes, BMC Bioinformatics, 2009
  • Giovanni Felici, Paola Bertolazzi, Guarracino M., Chinchuluun A, Pardalos P. M.: Logic formulas based knowledge discovery and its application to the classification of biological data, in the Proceedings of Biomat 2008: International Symposium On Mathematical And Computational Biology, Mondaini R.P. ed., 2009
  • Avenali A., Batini C., Paola Bertolazzi, Missier P.: Brokering infrastructure for minimum cost data procurement based on quality-quantity models, Decision Support Systems 45, 95-109, 2008
  • Paola Bertolazzi, Giovanni Felici, Festa P., Lancia G.: Logic Classification and Feature Selection for Biomedical Data, Computers & Mathematics with Applications 55(5), 889-899, 2008
  • Paola Bertolazzi, Godi A., Labbè M., Tininini L.: Solving haplotyping inference parsimony problem using a new basic polynomial formulation, Computers & Mathematics with Applications 55(5), 900-911, 2008
  • Tininini L., Paola Bertolazzi, Godi A., Lancia G.: CollHaps: A Heuristic Approach to Haplotype Inference by Parsimony, IEEE/ACM Transaction on Computational Biology and Bioinformatics, 2008
  • Paola Bertolazzi, Giovanni Felici: Learning to Classify Species with Barcodes, IASI-CNR, R. 665, 7/2007
  • Paola Bertolazzi, Giovanni Felici, Festa P.: Logic Based Methods for SNPs Tagging and Reconstruction, IASI-CNR, R. 667, 7/2007
  • Avenali A., Batini C., Paola Bertolazzi, Missier P.: A Formulation of the Data Quality Optimization Problem in Cooperative Information Systems, in the Proceedings of CAiSE Workshops (2), Grundspenkis J., Kirikova M. eds., 49-63, 2004
  • De Nicola A., Paola Bertolazzi, Michele Missikoff: Una Core Enterprise Ontology per l'organizzazione ed i sistemi di e-Business, in the Proceedings of 5{\textordmasculine} Workshop dei Docenti e Ricercatori di Organizzazione Aziendale, Roma 5-6 Febbraio, 2004, 2004
  • Paola Bertolazzi, De Santis L., Scannapieco M.: Automatic Record Matching in Cooperative Information Systems, DIS, Università di Roma ``La Sapienza'', 0, 2003
  • Becchetti L., Paola Bertolazzi, Carlo Gaibisso, Gambosi G.: On the design of efficient ATM routing schemes, Theoretical Computer Science 1-2, 341-359, 2002
  • Paola Bertolazzi, Di Battista G., Didimo W.: Quasi-Upward Planarity, Algorithmica 32, 474-506, 2002
  • Paola Bertolazzi, Di Serio P., Michele Missikoff: Techniche diagrammatiche nella rappresentazione della conoscenza d'impresa, AICA Rivista di Informatica 31, 2001
  • Paola Bertolazzi, Krusich C., Michele Missikoff: An Approach to the Definition of a Core Enterprise Ontology: CEO, in the Proceedings of OES-SEO'01 International Workshop, 2001
  • Paola Bertolazzi, Scannapieco M.: Introducing Data Quality in a Cooperative Context, in the Proceedings of Sixth International Conference on Information Quality, Mit Press Boston, MA, USA, 431-444, 2001
  • Paola Bertolazzi, Di Battista G., Didimo W.: Computing Orthogonal Drawings with the Minimum Number of Bends, IEEE Transactions on Computers 49, 826-840, 2000
  • Paola Bertolazzi, Di Serio P., Michele Missikoff: Tecniche diagrammatiche per la modellazione di impresa: una panoramica, AIIA Notizie 13, 24-33, 2000
  • Paola Bertolazzi, Fugini M.G., Pernici B.: Information System Design based on Reuse of Conceptual Components, in: Information Modelling in the Next Millenium, Rossi M. ed., IDEA group, 2000
  • Paola Bertolazzi, Di Battista G., Didimo W.: Quasi-upward planarity, in the Proceedings of 6-th International Symposium GD '98, Whitesides S.H. ed., Lecture Notes in Computer Science, 1574, Springer-Verlag, 15-29, 1998
  • Paola Bertolazzi, Di Battista G., Mannino C., Tamassia R.: Optimal upward planarity testing of single-source digraphs, SIAM Journal on Computing 27, 132-169, 1998
  • Paola Bertolazzi, Caterina De Simone, Anna Galluccio: A Nice Class for the Vertex Packing Problem, Discrete Applied Mathematics 76, 3-19, 1997
  • Paola Bertolazzi, Di Battista G., Didimo W.: Computing Orthogonal Drawings with the Minimum Number of Bends, in the Proceedings of Proceedings WADS'97, Lecture Notes in Computer Science, 1272, Springer-Verlag, 1997
  • Paola Bertolazzi, Di Battista G., Liotta G.: Parametric Graph Drawing, IEEE Transactions on Software Engineering 21, 662-673, 1995
  • Ligi A., Sara Nicoloso, Paola Bertolazzi, Cini M., Nobili P.: Formulazione e Risoluzione di un Problema di Controllo del Traffico Ferroviario, IASI-CNR,COllana Rapporti Interni RI.90, 1995
  • Paola Bertolazzi, Di Battista G., Liotta G., Mannino C.: Upward drawings of triconnected digraphs, Algorithmica, 476-497, 1994
  • Paola Bertolazzi, Di Battista G., Tamassia R., Tollis J.: How to draw a series-parallel digraph, International Journal of Computational Geometry & Applications, 385-402, 1994
  • Paola Bertolazzi, Caterina De Simone, Anna Galluccio: A nice class for the vertex packing problem, IASI-CNR, R. 358, 05/1993
  • Paola Bertolazzi, Di Battista G., Mannino C., Tamassia R.: Upward planarity testing of Single-Source digraphs, in the Proceedings of European Symposium on Algorithms, Lengauer T. ed., Lecture Notes in Computer Science, 726, 1993
  • Paola Bertolazzi, Di Battista G., Tamassia R., Tollis J.: How to draw a series-parallel digraph, in the Proceedings of Algorithm Theory-{SWAT92}, Lecture Notes in Computer Science, 621, Springer-Verlag, 1992
  • Cohen B., Di Battista G., Tamassia R., Tollis J., Paola Bertolazzi: A framework for dynamic graph drawing, in the Proceedings of ACM Computational Geometry, ACM Press, 1992
  • Beccaria M., Paola Bertolazzi, Di Battista G., Liotta G.: A tailorable and extensible automatic layout facility, in the Proceedings of IEEE Workshop on Visual Languages, 1991
  • Paola Bertolazzi, Di Battista G.: On upward drawing testing of triconnected digraphs, in the Proceedings of Computational Geometry, ACM Press, 272-180, 1991
  • Paola Bertolazzi, Concettina Guerra, Salza S.: An optimal parallel algorithm for the visibility problem from a point, Journal of Parallel and Distributed Computing 9, 11-14, 1990
  • Paola Bertolazzi, Concettina Guerra, Salza S.: A parallel algorithm for the visibility problem inside a single polygon, in the Proceedings of International Conference on Pattern Recognition, Springer-Verlag, 1989
  • Paola Bertolazzi, Sassano A.: A decomposition strategy for the vertex cover problem, Information Processing Letters (31), 299-304, 1989
  • Paola Bertolazzi, Concettina Guerra, Salza S.: A systematic design methodology for a dynamic programming systolic array, in the Proceedings of IEEE International Conference on Systolic Arrays, 453-462, 1988
  • Paola Bertolazzi, Sassano A.: A class of polynomially solvable set-covering problems, SIAM Journal on Discrete Mathematics 1 (3), 306-316, 1988
  • Paola Bertolazzi, Sassano A.: An O(mn) Algorithm for Regular Set-Covering Problems, Theoretical Computer Science 54, 237-247, 1987
  • Paola Bertolazzi: Dynamic programming procedures for SIMD architectures, in: Annals of discrete mathematics 25:Analysis and design of algorithms for combinatorial problems, Ausiello G., Lucertini M. eds., NORTH-HOLLAND, 47-63, 1985
  • Paola Bertolazzi, Bongiovanni G.: A VLSI structure for the deadlock avoidance problem, Journal of Parallel and Distributed Computing 1 (2), 352-361, 1985
  • Paola Bertolazzi, Luccio F. eds.: VLSI: algorithms and architectures, 1985
  • Ausiello G., Paola Bertolazzi: Parallel computation models: an Introduction, in the Proceedings of Algorithm design for computer sistem design, Springer-Verlag, 161-182, 1984
  • Paola Bertolazzi, Leporelli C., Lucertini M.: Alternative group relaxation of integer programming problems, Discrete Applied Mathematics 8, 143-151, 1984
  • Paola Bertolazzi, Pirozzi M.: A parallel algorithm for the optimal detection of a noisy curve, Computer Vision Graphics and Image Processing 27, 380-386, 1984
  • Paola Bertolazzi, Michele Missikoff, Terranova M.: CID: a VLSI Device for Lists Intersection, in: Database machines, Leilich H.O., Missikoff M. eds., Springer-Verlag, 188-204, 1983
  • Paola Bertolazzi, Lucertini M., Marchetti Spaccamela A.: Analysis of a class of graph partitioning problems, Rairo-Theoretical Informatics and Applications 16 (3), 255-261, 1982
  • Paola Bertolazzi, Pirozzi M.: Parallel algorithms for dynamic programming problems, in the Proceedings of II World Conference on Mathematics at the Service of Man, 139-145, 1982
  • Paola Bertolazzi, Lucertini M.: Task assignment in a multiprocessor system: a mathematical model, in the Proceedings of VIII Congresso IFAC, Pergamon Press, 1643-1647, 1981
  • Paola Bertolazzi, Lucertini M.: A conflict alert automated function for an air traffic control system, Journal of Navigation 33 (3), 475-481, 1980
  • Paola Bertolazzi, Bianco L., Ricciardelli S.: A method for determining the optimal districting in urban emergency services, Computers & Operations Research 4, 1-12, 1977
  • Paola Bertolazzi, Bianco L., Ricciardelli S.: An approach to the solution of the location problem in urban emergency services, in the Proceedings of IFAC Workshop on Application to Complex Analysis, Bielsko Biala, Giugno 1977, 33-38, 1977
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