Cinzia Volonté
Cinzia Volonté Cinzia Volonté
Senior Researcher
Dirigente di Ricerca

Unità di Ricerca "Fisiopatologia dello Shock", Università Cattolica del Sacro Cuore
Largo Agostino Gemelli, 8
00168 Roma - Italy

Office n. .
Tel.: 06 501703084
Personal web page: http://www.cnr.it/people/cinzia.volonte
email

Research interests

Main goals of current research in my lab are: -to understand the early and late events partaking to the neuronal and glial commitment to neurodegeneration and neuroinflammation; -to identify the molecular interactors and signalling pathways that regulate the purinergic and histaminergic involvement in ALS; -to use the knowledge of purinergic and histaminergic mechanisms to develop novel therapeutic strategies in particular against ALS.


Research groups

Selected publications
  • Coccurello R, Cinzia Volonté: P2X7 RECEPTOR IN THE MANAGEMENT OF ENERGY HOMEOSTASIS: IMPLICATIONS FOR OBESITY, DYSLIPIDEMIA AND INSULIN RESISTANCE, Frontiers in Endocrinology, 2020
  • Di Sante G, Amadio S, Sampaolese B, Clementi ME, Valentini MG, Cinzia Volonté, Casalbore P, Ria F, Michetti F: The S100B Inhibitor Pentamidine Ameliorates Clinical Score and Neuropathology of Relapsing— Remitting Multiple Sclerosis Mouse Model, Cells, Cellular and Molecular Mechanisms in Pathogenesis of Multiple Sclerosis, https://www.mdpi.com/2073-4409/9/3/748, 2020
  • Fabbrizio P, Apolloni S, Bianchi A, Salvatori I, Valle C, Lanzuolo C, Bendotti C, Nardo G, Cinzia Volonté: P2X7 activation enhances skeletal muscle metabolism and regeneration in SOD1G93A mouse model of amyotrophic lateral sclerosis, Brain Pathology 30(2), 272-282, 2020
  • Apolloni S, Caputi F, Pignataro A, Amadio S, Fabbrizio P, Ammassari-Teule M, Cinzia Volonté: Histamine Is an Inducer of the Heat Shock Response in SOD1-G93A Models of ALS., International Journal of Molecular Sciences, 20(15):3793, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696457/, 2019
  • Giacovazzo G, Fabbrizio P, Apolloni S, Coccurello R, Cinzia Volonté: Stimulation of P2X7 Enhances Whole Body Energy Metabolism in Mice, Frontiers in Cellular Neuroscience, 13:390, ://www.frontiersin.org/articles/10.3389/fncel.2019.00390/full, 2019
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