Simona Panunzi
Simona Panunzi Simona Panunzi
Researcher

Unità di Ricerca "Fisiopatologia dello Shock", Università Cattolica del Sacro Cuore
Largo Agostino Gemelli, 8
00168 Roma - Italy

Office n. 415
Tel.: +39 06 30155389
Fax: +39 06 3057845
email

Research groups

Selected publications
  • Alessandro Borri, Valerio Cusimano, Simona Panunzi, De Gaetano A.: Multi-agent system modeling of advection-diffusion-reaction equations, Proceedings of the 2019 European Control Conference (ECC 2019), Napoli, Italy, pp. 2430-2435, 2019
  • Alessandro Borri, Simona Panunzi, De Gaetano A.: Rapid and ultra-rapid insulin in glycemic control, Proceedings of the 2019 IEEE International Conference on Systems, Man, and Cybernetics (SMC 2019), Bari, Italia, pp. 346-351, 2019
  • Alessandro Borri, Cacace F., De Gaetano A., Germani A., Manes C., Palumbo P., Simona Panunzi, Pepe P.: Luenberger-Like Observers for Nonlinear Time-Delay Systems with Application to the Artificial Pancreas: The Attainment of Good Performance, IEEE Control Systems Magazine 37(4), pp. 33-49, 2017
  • Alessandro Borri, Palumbo P., Manes C., Simona Panunzi, De Gaetano A.: Sampled-data Observer-based Glucose Control for the Artificial Pancreas, Acta Polytechnica Hungarica vol. 14, p. 79-94, 2017
  • Gaz C., De Gaetano A., Manes C., Palumbo P., Alessandro Borri, Simona Panunzi: Effective Control of Glycemia using a Simple Discrete-delay Model, IFAC-PapersOnLine, Volume 50, Issue 1, Pages 13526-13531, 2017
  • Borri A, Simona Panunzi, Palumbo P., Manes C., De Gaetano A.: Glucose control with incomplete information, IEEE Conference on Systems, Man and Cybernetics, 2016
  • Alessandro Borri, Dimopoulos C., Simona Panunzi, Brancaleoni R., Gaz C., Gui D., Magalini S., De Gaetano A.: Modelling trauma physiology for large crisis management, 15th International Conference on Modeling and Applied Simulation (MAS 2016), Larnaca, Cipro, pp. 78-84, 2016
  • Alessandro Borri, Simona Panunzi, Brancaleoni R., Gui D., Magalini S., Gaz C., De Gaetano A.: Simulation of trauma incidents - Modelling the evolution of patients and resources, Journal of Medical Systems Vol. 40 (11): 234, Springer US, 2016
  • Alessandro Borri, Simona Panunzi, De Gaetano A.: A glycemia-structured population model, Journal of Mathematical Biology vol. 73(1): pp. 39-62, 2016
  • Alessandro Borri, Simona Panunzi, Palumbo P., Costanzo Manes, De Gaetano A.: Glucose control with incomplete information, Proceedings of the 2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC 2016), Budapest, Ungheria, pp. 1780-1784, 2016
  • Alessandro Borri, Simona Panunzi, Palumbo P., Costanzo Manes, De Gaetano A.: Preliminary results on glucose control with sampled information, IASI-CNR, R. 16-02, 2016
  • Cibella F., Cutitta G., Della Maggiore R., Ruggieri S., Simona Panunzi, De Gaetano A., Bucchieri S., Drago G., Melis MR, La Grutta S., Viegi G.: Effect of indoor nitrogen dioxide on lung function in urban environment, Environmental Research 138, 8-16, 2015
  • Pacciani E., Alessandro Borri, Soave P. M., Gui D., Magalini S., Simona Panunzi, Gaz C., Gaudio P., Malizia A., De Gaetano A.: Modelling and Simulation for Major Incidents - An Innovative Approach to Medical Response, Proceedings of the 2015 9th International Conference on Pervasive Computing Technologies for Healthcare, PervasiveHealth 2015, pp. 297-303, also published on the EAI Endorsed Transactions on Pervasive Health and Technology 15(4): e3, 2015
  • Simona Panunzi, De Gaetano A., Carnicelli A., Mingrone G.: Predictors of Remission of Diabetes Mellitus in Severely Obese Individuals Undergoing Bariatric Surgery: Do BMI or Procedure Choice Matter? A Meta-analysis, Annals of Surgery 261, 459-467, 2015
  • De Gaetano A., Simona Panunzi, Eliopoulos D., Hardy T., Mingrone G.: Mathematical Modeling of Renal Tubular Glucose Absorption after Glucose Load, Plos One 9, 2014
  • De Gaetano A., Simona Panunzi, Palumbo P., Gaz C., Hardy T.: Data-driven modeling of diabetes progression, in: Data-driven models for Diabetes. Diagnosis and Treatment, Mitsis G, Marmarelis V eds., Lecture Notes in Bioengineering, Springer-Verlag Berlin Heidelberg, 165-186, 2014
  • Palumbo P., Pepe P., Simona Panunzi, De Gaetano A.: DDE model-based control of glycemia via sub-cutaneous insulin administration, in: Delay Systems. From Theory to Numerics and Applications, Sipahi R, Vyhlidal T, Lafay J-F eds., Advances in Delays and Dynamics, 1, Springer International Publishing, 229-240, 2014
  • Palumbo P., Pizzichelli G, Simona Panunzi, Pepe P., De Gaetano A.: Closed-loop control scheme for the euglycemic hyperinsulinemic clamp: validation on virtual patients, IFAC World Congress on Automatic Control, 2014
  • Palumbo P., Pizzichelli G, Simona Panunzi, Pepe P., De Gaetano A.: Model-based control of plasma glycemia: Tests on populations of virtual patients, Mathematical Biosciences 257, 2-10, 2014
  • Simona Panunzi, Alessandro Borri, Palumbo P., Kovacs L, De Gaetano A.: Simulation of insulin regimen and glucose profiles in Type 1 Diabetic Patient, IEEE Conference on Systems, Man and Cybernetics, San Diego, USA, pp. 2464-2469, 2014
  • Simona Panunzi, De Gaetano A.: Pitfalls in Model Identification: Examples from Glucose-Insulin Modelling, in: Data-driven Modeling for Diabetes, Mitsis G, Marmarelis V eds., Lecture Notes in Bioengineering, Springer-Verlag Berlin Heidelberg, 117-129, 2014
  • Gui D., Magalini S., De Gaetano A., Simona Panunzi: Observational study on preoperative surgical field disinfection: Povidone-iodine and Chlorhexidine-alcohol, European review for medical and pharmacological sciences 17, 3367-3375, 2013
  • Palumbo P., Pepe P., Simona Panunzi, De Gaetano A.: Observer-based closed-loop control for the glucose-insulin system: local Input-to-State Stability with respect to unknown meal disturbances, American Control Conference (ACC13), 2013
  • Li J., Wang M., De Gaetano A., Palumbo P., Simona Panunzi: The range of time delay and the global stability of the equilibrium for an IVGTT model., Mathematical Biosciences 235, 128-137, 2012
  • Palumbo P., Pepe P., Simona Panunzi, De Gaetano A.: Observer-based glucose control via subcutaneous insulin administration, 8th IFAC Symposium on Biological and Medical Systems (BMS2012), 2012
  • Palumbo P., Pepe P., Simona Panunzi, De Gaetano A.: Time-delay model-based control of the glucose-insulin system, by means of a state observer, European Journal of Control, 2012
  • Palumbo P., Pepe P., Simona Panunzi, De Gaetano A.: Glucose control by subcutaneous insulin administration: a DDE modelling approach, in the Proceedings of 18th, IFAC World Congress on Automatic Control, 2011
  • Palumbo P., Pizzichelli G, Simona Panunzi, Pepe P., De Gaetano A.: Tests on a virtual patient for an observer-based, closed-loop control of plasma glycemia, 50th IEEE Conference on Decision and Control & 11th European Control Conference (CDC-ECC 2011), 2011
  • Manco M., Simona Panunzi, Macfarlane DP., Golay A., Melander O., Konrad T., Petrie JR., Mingrone G.: One-hour plasma glucose identifies insulin resistance and beta-cell dysfunction in individuals with normal glucose tolerance: cross-sectional data from the Relationship between Insulin Sensitivity and Cardiovascular Risk (RISC) study., Diabetes Care 33, 2090-2097, 2010
  • Simona Panunzi, De Gaetano A., Mingrone G.: Advantages of the single delay model for the assessment of insulin sensitivity from the intravenous glucose tolerance test., Theoretical Biology and Medical Modelling, 2010
  • Morganti A., Cilla S., Valentini V., Digesù C., Macchia G., Deodato F., Ferrandina G., Cece M.G., Cirocco M., Garganese G., Di Lullo L., Traficante D., Scarabeo F., Simona Panunzi, De Gaetano A., Sallustio G., Cellini N., Sofo L., Piermattei A., Scambia G.: Phase I-II Studies on Accelerated IMRT in Breast Carcinoma: Technical Comparison and Acute Toxicity in 332 Patients, Radiotherapy and Oncology 90, 86-92, 2009
  • Morganti A., Digesù C., Simona Panunzi, De Gaetano A., Macchia G., Deodato F., Cece M.G., Cirocco M., Di Castelnuovo A., Iacoviello L., Valentini V., Cellini N., De Gaetano G.: Radioprotective Effect of Moderate Wine Consumption in Patients With Breast Carcinoma, International Journal of Radiation Oncology Biology Physics 74, 1501-1505, 2009
  • Palumbo P., Pepe P., Simona Panunzi, De Gaetano A.: Robust closed-loop control of plasma glycemia: a discrete-delay model approach, Discrete and Continuous Dynamical Systems-Series B Special Issue on Mathematical Biology and Medicine, 455-468, 2009
  • Villa P., Costantini B, Suriano R., Perri C., Macri F., Ricciardi L., Simona Panunzi, Lanzone A.: The differential effect of the phytoestrogen genistein on cardiovascular risk factors in postmenopausal women: relationship with the metabolic status, Journal of Clinical Endocrinology and Metabolism 94, 552-558, 2009
  • Montalto M., Santoro L., Dalvai S., Curigliano V., D'Onofrio F., Scarpellini E., Cammarota G., Simona Panunzi, Gallo A., Gasbarrini A., Gasbarrini G.: Fecal Calprotectin Concentrations in Patients With Small Intestinal Bacterial Overgrowth., Digestive Diseases and Sciences 26, 183-186, 2008
  • Morganti A., Deodato F., Zizzari S., Cilla S., Digesù C., Macchia G., Simona Panunzi, De Gaetano A., Piermattei A., Cellini N., Valentini V.: Complexity Index (COMIX) and Not Type of Treatment Predicts Undetected Errors in Radiotherapy Planning and Delivery., Radiotherapy Oncology 89, 320-329, 2008
  • Montalto M., Santoro L., Curigliano V., D'Onofrio F., Cammarota G., Simona Panunzi, Ricci R., Gallo A., Grieco A., Gasbarrini A., Gasbarri G.: Faecal calprotectin concentrations in untreated coeliac patients, Scandinavian Journal of Gastroenterology 42, 957-961, 2007
  • Palumbo P., Simona Panunzi, De Gaetano A.: Qualitative behavior of a family of delay-differential models of the glucose-insulin system, Discrete and Continuous Dynamical Systems-Series B 7 (2), 399-424, 2007
  • Simona Panunzi, Palumbo P., De Gaetano A.: A discrete single-delay model for the Intra-Venous Glucose Tolerance Test, Theoretical Biology and Medical Modelling 4 (35), 2007
  • Sizzi O., Rossetti A., Malzoni M., Minelli L., La Grotta F., Soranna L., Simona Panunzi, Spagnolo R., Imperato F., Landi S., Fiaccamento A., Stola E.: Italian multicenter study on complications of laparoscopic myomectomy, Journal of Minimally Invasive Gynecology 14, 453-462, 2007
  • De Gaetano A., Simona Panunzi, Beck B., Boulanger B.: Statistical Modeling in Pharmaceutical Research \& Development, in: Computers in Drug Discovery, Ekins S. ed., John Wiley, 2006
  • Gui D., Mingrone G., Valenza V., Spada P.L., Mutignani M., Runfola M., Scarfone A., Di Mugno M., Simona Panunzi: Effect of botulinum toxin antral injection on gastric emptying and weight reduction in obese patients: a pilot study, Alimentary Pharmacology & Therapeutics 23 (5), 675-80, 2006
  • Palumbo P., Ong-Clausen W.H., Simona Panunzi, De Gaetano A.: Linear periodic models of subcutaneous insulin absorption: mathematical analysis, HERMIS Journal 7, 60-79, 2006
  • Pavoni E., Pucci A., Vaccaro P., Monteriu G., Ceratti Ade P., Lugini A., Virdis R.A., Cortesi E., De Gaetano A., Simona Panunzi, Felici F., Minenkova O.: A study of the humoral immune response of breast cancer patients to a panel of human tumor antigens identified by phage display, Cancer Detection and Prevention 30 (3), 248-256, 2006
  • Rusciani L., Proietti I., Rusciani A., Paradisi A., Sbordoni G., Alfano C., Simona Panunzi, De Gaetano A., Lippa S.: Low plasma coenzyme Q10 levels as an independent prognostic factor for melanoma progression, Journal of the American Academy of Dermatology 54 (2), 234-241, 2006
  • Ciampelli M., Leoni F., Cucinelli F., Mancuso S., Simona Panunzi, De Gaetano A., Lanzone A.: Assessment of Insulin Sensitivity From Measurements in the Fasting State and During an Oral Glucose Tolerance Test in Polycystic Ovary Syndrome and Menopausal Patients, Journal of Clinical Endocrinology and Metabolism 90, 1398-1406, 2005
  • De Gaetano A., Simona Panunzi: Nonlinear Estimation and Confidence Regions: a Biological Case Study, in: Mathematical Models for Bioengineering and Probabilistic Systems, Misra J.C. ed., Narosa, New Delhi, 2005
  • Simona Panunzi, De Gaetano A., Mingrone G.: Approximate Linear Confidence and Curvature of a Kinetic Model of Dodecanedioic Acid in Humans, American Journal of Physiology-Endocrinology and Metabolism, 2005
  • Picchini U., De Gaetano A., Simona Panunzi, Ditlevsen S., Mingrone G.: A mathematical model of the euglycemic hyperinsulinemic clamp, Theoretical Biology and Medical Modelling 2, 2005
  • Ruzzo A., Graziano F., Pizzagalli F., Santini D., Battistelli V., Simona Panunzi, Canestrari E., Catalano V., Humar B., Ficarelli R., Bearzi I., Cascinu S., Naldi N., Testa E., Magnani M.: Interleukin 1B Gene (IL-1B) and Interleukin 1 Receptor Antagonist Gene (IL-1RN) Polymorphisms in Helicobacter Pylori-Negative Gastric Cancer of Intestinal and Diffuse Histotype, Annals of Oncology 16, 887-892, 2005
  • Villa P., Perri C., Suriano R., Cucinelli F., Simona Panunzi, Ranieri M., Mele C., Lanzone A.: L-Folic Acid Supplementation in Healthy Postmenopausal Women: Effect on Homocysteine and Glycolipid Metabolism, Journal of Clinical Endocrinology and Metabolism 90, 4622-4629, 2005
  • Ciampelli M., Leoni F., Cucinelli F., Mancuso S., Simona Panunzi, De Gaetano A., Lanzone A.: Assessment of Insulin Sensitivity From Measurements in the Fasting State and During an Oral Glucose Tolerance Test in Polycystic Ovary Syndrome and Menopausal Patients., Journal of Clinical Endocrinology and Metabolism, 2004
  • Graziano F., Kawakami K., Watanabe G., Ruzzo A., Humar B., Santini D., Catalano V., Ficarelli R., Merriman T., Simona Panunzi, Testa E., Cascinu S., Bearzi I., Tonini G., Magnani M.: Association of Thymidylate Synthase Polymorphisms With Gastric Cancer Susceptibility., International Journal of Cancer 112, 1010-1014, 2004
  • Rossi L., Castro M., D'Orio F., Damonte G., Serafini S., Bigi L., Panzani I., Novelli G., Dallapiccola B., Simona Panunzi, Di Carlo P., Bella S., Magnani M.: Low Doses of Dexamethasone Constantly Delivered by Autologous Erythrocytes Slow the Progression of Lung Disease in Cystic Fibrosis Patients., Blood Cells Molecules and Diseases 33, 57-63, 2004
  • Runfola M., Rossi S., Simona Panunzi, Spada P.L., Gui D.: Botulinum Toxin in Gastric Submucosa Reduces Stimulated HCl Production in Rats, BMC Gastroenterology 26 (3), 2003
  • Gui D., Runfola M., Rossi S., Simona Panunzi, De Gaetano A.: Academic recruitment in Spain and Italy, Science 297 (5582), 770-771, 2002
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