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Federico Papa
Researcher
Biomedical Engineer
Istituto di Analisi dei Sistemi ed Informatica "Antonio Ruberti"
Via dei Taurini, 19
00185 Roma - Italy
Office n. 405
Tel.: +39 06 4993 7143
Fax: +39 06 4993 7137

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Research interests
Mathematical Modeling of Biological Systems; Systems Biology; Dynamic System Identification and Filtering; Optimal Control Theory
Research groups
Selected publications
- Bertuzzi A, Federica Conte, Federico Papa, Carmela Sinisgalli: Applications of nonlinear programming to the optimization of fractionated protocols in cancer radiotherapy, Information, 2020
- Di Giamberardino P., Iacoviello D., Federico Papa, Carmela Sinisgalli: Dynamical evolution of COVID-19 in Italy with an evaluation of the size of the asymptomatic infective population, IEEE Journal of Biomedical and Health Informatics, 2020
- Gaglio D., Bonanomi M., Valtorta S., Bharat R., Ripamonti M., Federica Conte, Fiscon G., Righi N., Napodano E., Federico Papa, Raccagni I., Parker S.J., Cifola I., Camboni T., Paci P, Colangelo A.M., Vanoni M., Metallo C.M., Moresco R.M., Alberghina L.: Disruption of redox homeostasis for combinatorial drug efficacy in K-Ras tumors as revealed by metabolic connectivity profiling, Cancer & Metabolism, 2020
- Bruni C., Federica Conte, Federico Papa, Carmela Sinisgalli: Optimal number and sizes of the doses in fractionated radiotherapy according to the LQ model, Mathematical Medicine and Biology 36, 1-53, 2019
- Pasquale Palumbo, Federico Papa, Vanoni M., Alberghina L.: Qualitative behavior of a coarse-grain growth model, presented at INES 2019, 2019
- Federico Papa, Giovanni Felici, Franzetti M, Gandolfi A., Carmela Sinisgalli: Impact of ART-induced viral suppression on the HIV epidemic in Italy, Mathematical Medicine and Biology, 2019
- Cacace F., Valerio Cusimano, Germani A., Pasquale Palumbo, Federico Papa: Closed-loop control of tumor growth by means of anti-angiogenic administration, Mathematical Biosciences and Engineering 15, 827-839, 2018
- Pasquale Palumbo, Federico Papa: Mathematical Modeling in Systems Biology, Minisymposium at SIMAI 2018, 2018
- Pasquale Palumbo, Vanoni M., Federico Papa, Busti S, Wortel M., Teusink B, Alberghina L.: An integrated model of metabolism, growth and cell cycle in budding yeast, presented at SIMAI 2018, 2018
- Pasquale Palumbo, Vanoni M., Federico Papa, Busti S, Wortel M., Teusink B, Alberghina L.: An integrated model quantitatively describing metabolism, growth and cell cycle in budding yeast, Communications in Computer and Information Science, Artificial Life and Evolutionary Computation, 12th Italian Workshop, WIVACE 2017, Venice, Italy, September 19-21, 2017, Revised Selected Papers, 2018
- Pasquale Palumbo, Vanoni M., Federico Papa, Busti S., Alberghina L.: Whole yeast model: what and why?, presented at Bioinformatics and Computational Biology International Conference 2018, 2018
- Federico Papa, Binda F, Giovanni Felici, Franzetti M, Gandolfi A., Carmela Sinisgalli, Balotta C: A simple model of HIV epidemic in Italy: the role of the anti-retroviral treatment, Mathematical Biosciences and Engineering 15, 181-207, 2018
- Pasquale Palumbo, Vanoni M., Federico Papa, Busti S, Wortel M., Teusink B, Alberghina L.: An integrated metabolism, growth and cell cycle model quantitatively describing budding yeast growth, presented at WIVACE 2017, 2017
- Federico Papa, Balotta C, Giovanni Felici, Franzetti M, Gandolfi A., Servilio M., Carmela Sinisgalli: Partial vs. complete response to antiretroviral treatments in a model of the HIV epidemic in Italy, presented at MOBI 2017, 2017
- Bertuzzi A., Federica Conte, Mingrone G., Federico Papa, Salinari S., Carmela Sinisgalli: Insulin Signaling in Insulin Resistance States and Cancer: A Modeling Analysis, Plos One, http://dx.doi.org/10.1371/journal.pone.0154415, 2016
- Bruni C., Federica Conte, Federico Papa, Carmela Sinisgalli: Optimal number and sizes of the doses in fractionated radiotherapy, IASI-CNR, R. 16-06, 9/2016
- Valerio Cusimano, Pasquale Palumbo, Federico Papa: Closed-loop control of tumor growth by means of anti-angiogenic administration, presented at SIMAI 2016, 2016
- Federico Papa, Binda F, Giovanni Felici, Franzetti M, Gandolfi A., Carmela Sinisgalli, Balotta C: A simple model of HIV epidemic in Italy: the role of the anti-retroviral treatment, IASI-CNR, R. 16-05, 9/2016
- Federico Papa, Binda F, Giovanni Felici, Franzetti M, Gandolfi A., Carmela Sinisgalli, Balotta C: A simple model of HIV epidemic in Italy: the role of the anti-retroviral treatment, presented at SIMAI 2016, 2016
- Bruni C, Federica Conte, Federico Papa, Carmela Sinisgalli: Optimal weekly scheduling in fractionated radiotherapy: effect of an upper bound on the dose fraction size, Journal of Mathematical Biology, 2015
- Federica Conte, Federico Papa, Carmela Sinisgalli: Minimum value of the maximal entry of n-dimensional vectors with constant sum of the entries and of the squared entries, IASI-CNR, R. 15-10, 2015
- Valerio Cusimano, Pasquale Palumbo, Federico Papa: Closed-loop control of tumor growth by means of anti-angiogenic administration, IEEE 54th Annual Conference on Decision and Control (CDC 2015), 2015
- Pasquale Palumbo, Vanoni M., Federico Papa, Alberghina L.: A Growth and Cycle Model for Saccharomyces cerevisiae, presented at 27th International Conference on Yeast Genetics and Molecular Biology, poster session, 2015
- Federico Papa, Binda F, Giovanni Felici, Franzetti M, Gandolfi A., Carmela Sinisgalli, Balotta C: A simple model of HIV epidemic in Italy: the role of the anti-retroviral treatment, presented at Mathematical and Computational Epidemiology of Infectious diseases 2015, 2015
- Federico Papa, Pasquale Palumbo, Vanoni M., Wortel M., Teusink B, Alberghina L.: An Integrated Metabolism, Growth and Cycle Model for Saccharomyces cerevisiae: Validation against Chemostat Data, presented at 27th International Conference on Yeast Genetics and Molecular Biology, poster session, 2015
- Vanoni M., Pasquale Palumbo, Federico Papa, Busti S., Wortel M., Teusink B, Alberghina L.: An integrated metabolism, growth and cycle model for Saccharomyces cerevisiae, presented at 27th International Conference on Yeast Genetics and Molecular Biology, 2015
- Bertuzzi A., Bruni C., Federico Papa, Carmela Sinisgalli: Optimal solution for a cancer radiotherapy problem, Journal of Mathematical Biology 66, 311-349, 2013
- Bruni C., Koch G., Federico Papa: Estimate accuracy versus measurement cost saving in continuous time linear filtering problems, Journal of the Franklin Institute-Engineering and Applied Mathematics 350, 1051-1074, 2013
- Federico Papa, Conte Federica: Minimal value of the maximal dose fraction in the optimization of the radiotherapy scheduling, Dipartimento di Ingegneria Informatica, Automatica e Gestionale ``A. Ruberti'', Sapienza Università di Roma, 13000, 2013
- Bertuzzi A., Bruni C., Federico Papa, Carmela Sinisgalli: Optimal solution for a cancer radiotherapy problem, IASI-CNR, R. 11-18, 2011
- Bertuzzi A., Bruni C., Federico Papa, Carmela Sinisgalli: Optimal solution for a cancer radiotherapy problem, presented at CIMAB & GASVA SIMAI Young Researcher Workshop, 2011
- Bruni C., Koch G., Federico Papa: A measurement policy in stochastic linear filtering problems, Computers & Mathematics with Applications 61, 546-566, 2011
- Bruni C., Koch G., Federico Papa: Measurement Saving Versus Estimate Accuracy in Linear Filtering Problems, IFAC Proceedings Volumes, 44, 2011
- Federico Papa, Carmela Sinisgalli: Optimal solution for a cancer radiotherapy problem with a maximal damage constraint on normal tissues, IASI-CNR, R. 11-20, 2011
- Bertuzzi A., Bruni C., Fasano A., Gandolfi A., Federico Papa, Carmela Sinisgalli: Response of tumor spheroids to radiation: modeling and parameter estimation, Bulletin of Mathematical Biology 72, 1069-1091, 2010
- Federico Papa: A model of the tumour spheroid response to radiation: identifiability analysis, BIOSIGNALS 2010, Proceeding of the 3rd International Conference on Bio-Inspired Systems and Signal Processing, 2010
- Bertuzzi A., Bruni C., Fasano A., Gandolfi A., Federico Papa, Carmela Sinisgalli: Response of tumour spheroids to radiation: modelling and parameter estimation, IASI-CNR, R. 09-16, 2009
- Federico Papa: Models of tumour spheroid response to radiation: identifiability analysis, Dipartimento di Informatica e Sistemistica "Antonio Ruberti", 9000, 2009
- Bertuzzi A., Bruni C., Fasano A., Gandolfi A., Federico Papa, Carmela Sinisgalli: A mathematical model for the radiation response of tumour spheroids, presented at SIMAI 9th Congress, 2008
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