Publications of Concettina Guerra

This page shows all publications that appeared in the IASI annual research reports. Authors currently affiliated with the Institute are always listed with the full name.

You can browse through them using either the links of the following line or those associated with author names.

Show all publications of the year  ALL, with author Guerra C., in the category IASI Research Reports (or show them all):


IASI Research Report n. 12-18  (Previous    Next)  

Paola Bertolazzi, Bock M.E., Guerra C.

On the functional and structural characterization of hubs in protein-protein interaction networks

ABSTRACT
A number of interesting issues have been addressed on biological networks about their global and local properties. The connection between the topological properties of proteins in Protein-Protein Interaction (PPI) networks and their biological relevance has been investigated focusing on hubs, i.e. proteins with a large number of interacting partners. We will survey the literature trying to answer the following questions: Do hub proteins have special biological properties? Do they tend to be more essential than non-hub proteins? Are they more evolutionarily conserved? Do they play a central role in modular organization of the protein interaction network? Are there structural properties that characterize hub proteins?
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