

PASQUALE PALUMBO HOME PAGE  
COLLOQUIA@IASI 

POSITION EDUCATION
TEACHING RESEARCH
PUBLICATIONS
CURRICULUM 




Versione in italiano
last changes: 19/11/18
BIOGRAPHICAL SKETCH Pasquale Palumbo was born in Pescara, Italy, December 18, 1970 He is married and lives in Pescara. Ph.D. in Electronic Engineering, February 10, 2000 CNR Researcher, since March 2005 


Researcher at the Institute
of System Analysis and Computer Science (IASI
"Antonio Ruberti")
of the CNR in Rome, Italy, since
March 22, 2005, Research Groups of:
"Systems
and Control Theory", "Computational and Systems Biology" at
Viale ManzoniAddress: Via dei Taurini 19, 00185 Rome. Ph.: +39 06 4993 7134 "Mathematical Modeling in Biology and Medicine" at BioMathematics Laboratory Address: Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, 00168 Rome Ph.: +39 06 30155389 Fax: +39 06 3057845 Email: pasquale.palumbo@iasi.cnr.it POSITIONS SERVED
Research Associate at the Institute
of System Analysis and Computer Science (IASI
"Antonio Ruberti") of the CNR in Rome, Italy, (May 20, 2000
 March 21,2005).






TEACHING ACTIVITY




Didactic
Publications (in Italian):

SYSTEM THEORY – Prof.
C. Manes Information and Control Engineering Electronic Engineering Telecommunication Engineering SYSTEM THEORY – Prof. P. Pepe Management Engineering 
NEW EDITION: More
than 100 exercises all endowed with solutions above
timeinvariant finitedimensional linear systems:




RESEARCH TOPICS The research activity may be split into two main branches: one concerning theoreticalmethodological research in automaticl control, the other devoted to mathematical modeling in biology and medicine and Systems Biology THEORETICAL METHODOLOGICAL RESEARCH IN AUTOMATIC CONTROL
MATHEMATICAL MODELING IN BIOLOGY AND MEDICINE (research activity developed at the BioMatLab of IASI, located at the Policlinico Gemelli Hospital)
SYSTEMS BIOLOGY (research activity mainly developed within the Research Infrastructure "SYSBIO, Centre of Systems Biology", Principal Investigator of Research Unit RU09)


PUBLICATIONS
ON INTERNATIONAL JOURNALS R[1] A. Germani, C. Manes, P. Palumbo, ''Optimal linear filtering for bilinear stochastic differential systems with unknown inputs'', IEEE Trans. on Automatic Control, Vol. 47, No. 10, pp. 17261730, 2002 R[2] A. Germani, C. Manes, P. Palumbo, ''Polynomial filtering for stochastic non Gaussian descriptor systems'', IEEE Trans. on Circuits and Systems  I: Regular Papers, Vol. 51, No. 8, pp. 15611576, 2004 R[3] A. Germani, C. Manes, P. Palumbo, ''Polynomial Extended Kalman Filter'', IEEE Trans. on Automatic Control, Vol. 50, No. 12, pp. 20592064, 2005 R[4] A. Germani, C. Manes, P. Palumbo, ''Filtering for bimodal systems:
the case of unknown switching systems'', IEEE
Trans. on Circuits
and
Systems  I: Regular Papers, Vol.
53, No. 6, pp. 12661277, 2006
R[5] P. Palumbo, W.H. OngClausen, S.
Panunzi, A. De Gaetano, ''Linear periodic models of
subcutaneous insulin absorption: mathematical
analysis'', HERMIS
Journal, Special Issue on Differential and
Integral Equations in Physics Epidemiology and
Medicine: Application and Numerics, Vol. 7, pp. 6079, 2006
R[6] A. Germani, C. Manes, P. Palumbo, M.
Sciandrone, ''A
higherorder method for the solution of nonlinear scalar
equation'', Journal of Optimization Theory and
Applications, Vol. 131, No. 3, pp. 347364, 2006R[7] A. Germani, C. Manes, P. Palumbo, P. Pepe, ''A robust approximation scheme for the LQG control of an undamped flexible beam with a tip mass'', European Journal of Control, Vol.12, No.6, pp. 635651, 2006 R[8] P. Palumbo, S. Panunzi, A. De Gaetano, ''Qualitative behavior of a family of delaydifferential models of the glucoseinsulin system'', Discrete and Continuous Dynamical Systems  Series B, Vol. 7, No. 2, pp. 399424, 2007 R[9] S. Panunzi, P. Palumbo, A. De Gaetano, ''A discrete singledelay model for the Intra Venous Glucose Tolerance Test'', Theoretical Biology and Medical Modelling, Vol. 4, No. 35, 16 pages, 2007 R[10] A. Germani, C. Manes, P. Palumbo, ''Filtering of stochastic nonlinear differential systems via a Carleman approximation approach'', IEEE Trans. on Automatic Control, Vol. 52, No. 11, pp. 21662172, 2007 R[11] P. Palumbo, U. Picchini, B. Beck, J. Van Gelder, N. Delbar, A. De Gaetano, ''A general approach to the apparent permeability index'', Journal of Pharmacokinetics and Pharmacodynamics, Vol.35, pp.235248, 2008 R[12] D.V. Giang, Y. Lenbury, A. De Gaetano, P. Palumbo, ''Delay model of glucoseinsulin systems: global stability and oscillated solutions conditional on delays'', Journal of Mathematical Analysis and Applications, Vol.343, Issue 2, pp.9961006, 2008 R[13] A. De Gaetano, T. Hardy, B. Beck, E. AbuRaddad, P. Palumbo, J. BueValleskey, N. Porksen, "Mathematical models of diabetes progression'', American Journal of Physiol. Endocrinol. Metab., Vol.295, pp.E1462E1479, 2008 R[14] A. Germani, C. Manes, P. Palumbo, ''State estimation of stochastic systems with switching measurements: a polynomial approach'', International Journal of Robust and Nonlinear Control, Vol.19, Issue 14 (Special Issue on "Observability and observerbased control of hybrid systems"), pp.16321655, 2009 R[15] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''Robust closedloop control of plasma glycemia: a discretedelay model approach'', Discrete and Continuous Dynamical Systems  Series B, Special Issue on Mathematical Biology and Medicine, Vol.12, No.2, pp.455468, 2009 R[16] P. Palumbo, A. De Gaetano, ''An islet population model of the endocrine pancreas'', Journal of Mathematical Biology, Vol.61, No.2, pp.171205, 2010 R[17] A. Germani, C. Manes, P. Palumbo, ''Representation of a class of MIMO systems via internally positive realization'', European Journal of Control, Vol.16, No.3, pp.291304, 2010 R[18] G. Mavelli, P. Palumbo, ''The Carleman approximation approach to solve a stochastic nonlinear control problem'', IEEE Trans. on Automatic Control, Vol.55, No.4, pp.976982, 2010 R[19] L. Farina, A. Germani, G. Mavelli, P. Palumbo, ''Identification of regulatory network motifs from gene expression data'', Journal of Mathematical Modelling and Algorithms, Vol. 9, No.3, pp.233245, 2010 R[20] P. Palumbo, G. Mavelli, L. Farina, L. Alberghina, ''Networks and circuits in cell regulation'', Biochemical and Biophysical Research Communications, Vol. 396, pp.881886, 2010 R[21] F. Muzi, A. De Sanctis, P. Palumbo, ''A new algorithm for smart grid protection based on synchronized sampling'', International Journal of Energy and Environment, Vol. 5, Issue 4, pp.566573, 2011 R[22] L. Alberghina, G. Mavelli, G. Drovandi, P. Palumbo, S. Pessina, F. Tripodi, P. Coccetti, M. Vanoni, "Growth and cycle in Saccharomyces cerevisiae: Basic regulatory design and proteinprotein interaction network'', Biotechnology Advances, Vol. 30, Issue 1, pp.5272, 2012 R[23] J. Li, M. Wang, A. De Gaetano, P. Palumbo, S. Panunzi, ''The range of time delay and the global stability of the equilibrium for an IVGTT model'', Mathematical Biosciences, Vol.235, Issue 2, pp.128137, 2012 R[24] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''Timedelay modelbased control of the glucoseinsulin system, by means of a state observer'', European Journal of Control, Vol.18(6), pp.591606, 2012 R[25] A. De Gaetano, A. Matone, A.M. Agnes, P. Palumbo, F. Ria, S. Magalini, ''Modeling rejection immunity'', Theoretical Biology and Medical Modeling, Vol. 9(18), 30 pages, 2012 R[26] F. Cacace, A. Germani, P. Palumbo, ''The state observer as a tool for the estimation of gene expression'', Journal of mathematical Analysis and Applications, Vol. 391, pp.382396, 2012 R[27] F. Cacace, A. Germani, P. Palumbo, ''The Observer Follower Filter: a new approach to nonlinear suboptimal filtering'', Automatica, Vol. 49(2), pp.548553, 2013 R[28] K. Juagwon, Y. Lenbury, A. De Gaetano, P. Palumbo, ''Application of modified Watanabe's approach for reconstruction of insulin secretion rate during OGTT under nonconstant fraction of hepatic insulin extraction'', International Journal of Mathematics and Computers in Simulation, Vol.7(3), pp.304313, 2013 R[29] P. Palumbo, S. Ditlevsen, A. Bertuzzi, A. De Gaetano, ''Mathematical modeling of the glucoseinsulin system: a Review'', Mathematical Biosciences, Vol.244, pp.6981, 2013 R[30] F. Carravetta, P. Palumbo, P. Pepe, ''Memoryless solution to the optimal control problem for linear systems with delayed input'', Kybernetyca, Vol.49(4), pp.569589, 2013 R[31] S. Tasdighian, L. Di Paola, M. De Ruvo, P. Paci, D. Santoni, P. Palumbo, G. Mei, A. Di Venere, A. Giuliani, ''Modules identification in protein structures: the topological and geometrical solutions", Journal of Chemical Information and Modeling, Vol. 54, pp.159168, 2014 R[32] P. Palumbo, G. Pizzichelli, S. Panunzi, P. Pepe, A. De Gaetano, ''Modelbased control of plasma glycemia: tests on populations of virtual patients", Mathematical Biosciences, Vol. 257, pp.210, 2014 R[33] A. De Gaetano, C. Gaz, P. Palumbo, S. Panunzi, ''A unifying organ model of pancreatic insulin secretion'', PLoS ONE, 10(11): e0142344, 34 pages, 2015 R[34] A. Borri, F. Carravetta, G. Mavelli, P. Palumbo, ''Blocktridiagonal statespace realization of Chemical Master Equations: a tool to compute explicit solutions", Journal of Computational and Applied Mathematics, Vol. 296, pp.410426, 2016 R[35] P. Palumbo, M. Vanoni, V. Cusimano, S. Busti, F. Marano, L. Alberghina, ''Whi5 phosphorylation embedded in the G1/S network dynamically controls critical cell size and cell fate'', Nature Communications, 7:11372, doi: 10.1038/ncomms11372, 2016 R[36] A. Borri, P. Palumbo, A. Singh, ''The impact of negative feedback in metabolic noise propagation'', IET Systems Biology, Vol.10, pp.179186, 2016 R[37] F. Cacace, V. Cusimano, A. Germani, P. Palumbo, ''A state predictor for continuoustime stochastic systems'', Systems & Control Letters, Vol.98, pp.3743, 2016 R[38] A. Borri, P. Palumbo, C. Manes, S. Panunzi, A. De Gaetano, ''Sampleddata observerbased glucose control for the Artificial Pancreas'', Acta Polytechnica Hungarica, Vol.14(1), pp.7994, 2017 R[39] A. Borri, F. Cacace, A. De Gaetano, A. Germani, C. Manes, P. Palumbo, S. Panunzi, P. Pepe, ''Luenbergerlike observers for nonlinear timedelay systems with application to the Artificial Pancreas: the attainment of good performance'', IEEE Control Systems Magazine, Vol.37(4), pp.3349, 2017 R[40] C. Manes, P. Palumbo, V. Cusimano, M. Vanoni, L. Alberghina, ''Modeling biological timing and synchronization mechanisms by means of interconnections of stochastic switches'', IEEE Control Systems Letters, Vol.2(1), pp.1924, 2017 (accepted for presentation at 56th IEEE conference of Decision and Control, Melbourne, Australia, December 2017) R[41] F. Cacace, V. Cusimano, A. Germani, P. Palumbo, F. Papa, ''Closedloop control of tumor growth by means of antiangiogenic administration'', Mathematical Biosciences and Engineering, Vol.15(4), pp.827839, 2018 R[42] F. Cacace, V. Cusimano, P. Palumbo, ''Optimal impulsive control with application to antiangiogenic tumor therapy'', to appear on IEEE Trans. on Control Systems Technology, 2018 R[43] M. Di Ferdinando, P. Pepe, P. Palumbo, S. Panunzi, A. De Gaetano, ''Semiglobal sampleddata dynamic output feedback controller for the glucoseinsulin system'', to appear on IEEE Trans. on Control Systems Technology, 2018 OTHER PUBLICATIONS ON INTERNATIONAL JOURNALS Ra[1] A. De Gaetano, T. Hardy, E. AbuRaddad, P. Palumbo, J. BueValleskey, N. Porksen, "Predicting the effects of lifestyle of pharmacological intervention on progression of type 2 diabetes: evaluation of a novel mathematical model against results of the DPP'', Diabetologia, Vol.52, Suppl.1, pp.S328S328, 2009 B[1] P.
Palumbo, A. De Gaetano, ''Statefeedback control
of the glucoseinsulin system", MATH
EVERYWHERE. Deterministic and Stochastic
Modelling in Biomedicine, Economics and Industry.
G. Aletti, M. Burger, A. Micheletti, D. Morale Editors,
Springer, Heidelberg, pp. 241252, 2006
B[3] A. De Gaetano, S. Panunzi, P. Palumbo, C. Gaz, T. Hardy, ''Datadriven modeling of diabetes
progression", Datadriven
modeling
for diabetes. Diagnosis and Treatment. Lectures Notes
in Bioengineering. V. Marmarellis,
G. Mitsis Editors, Springer Verlag Berllin
Heidelberg, pp. 165186, 2014B[2] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''DDE modelbased control of glycemia via subcutaneous insulin administration", Delay Systems. From Theory to Numerics and Applications. T. Vyhidal, J.F Lafay, R. Sipahi Editors, Springer International Publishing, pp. 229240, 2014 B[4] J.D. Kong, S.S. Kumar, P. Palumbo, ''DDE models of the glucoseinsulin system: a useful tool for the artificial pancreas", Managing Complexity, Reducing Perplexity in Biological Systems. M. Delitala, G. AjomneMarsan Editors, Springer Proceedings in Mathematics & Statistics, Vol. 67, pp. 109117, 2014 B[5] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, '' Recent results on glucoseinsulin predictions by means of a state observer for timedelay systems", Prediction Methods for Blood Glucose Concentration: Design, Use and Evaluation. H. Kirchsteiger et al Editors, Springer Lecture Notes in Bioengineering, pp.227241, 2015 B[6] P. Palumbo, M. Vanoni, F. Papa, S. Busti, M. Wortel, B. Teusink, L. Alberghina, ''An integrated model quantitatively describing metabolism, growth and cell cycle in budding yeast", Artificial Life and Evolutionary Computation, M. Pelillo et al Editors, Communications in Computer and Information Science (CCIS book series), Springer, pp.165180, 2018 PUBLICATIONS ON THE PROCEEDINGS OF
INTERNATIONAL CONFERENCES
C[1] M. Dalla Mora, C. Manes, P. Palumbo, ''Optimal quadratic filtering of quantization noise in nonGaussian systems'', UKACC International Conference on Control 96, pp. 10911096, Exeter, UK, 1996 C[2] C. Manes, P. Palumbo, P. Pepe, ''An approximation scheme for the LQG control of flexible structures'', 5th European Control Conference (ECC99), Karlsruhe, Germany, 1999 C[3] P. Palumbo, ''A realizable observer for a flexible system with delayed outputs'', 2nd IFAC Workshop on Linear Time Delay Systems (LTDS2000), pp. 6469, Ancona, Italy, 2000 C[4] A. Germani, C. Manes, P. Palumbo, ''Optimal linear filtering for stochastic nonGaussian descriptor systems'', 40th Conference on Decision and Control (CDC01), pp. 25142519, Orlando, Florida, 2001 C[5] A. Germani, C. Manes, P. Palumbo, ''Kalman Bucy filtering for linear stochastic differential systems with unknown inputs'', 15th IFAC World Congress on Automatic Control (IFAC2002), Barcelona, Spain, 2002 C[6] A. Germani, C. Manes, P. Palumbo, ''Filtering switching systems via a singular minimax approach'', 41st Conference on Decision and Control (CDC02), pp. 26002605, Las Vegas, Nevada, 2002 C[7] A. Germani, C. Manes, P. Palumbo, ''State estimation for a class of stochastic variable structure systems'', 41st Conference on Decision and Control (CDC02), pp. 30273032, Las Vegas, Nevada, 2002 C[8] A. Germani, C. Manes, P. Palumbo, ''A minimum variance filter for discrete time linear systems perturbed by unknown nonlinearities'', IEEE International Symposium on Circuits and Systems (ISCAS2003), Bangkok, Thailand, 2003 C[9] A. Germani, C. Manes, P. Palumbo, ''Polynomial extended Kalman filtering for discretetime nonlinear stochastic systems'', 42nd Conference on Decision and Control (CDC03), pp. 886891, Maui, Hawaii, 2003 C[10] A. Germani, C. Manes, P. Palumbo,
''Polynomial filtering for stochastic systems with
Markovian switching coefficients'', 42nd
Conference on Decision and Control (CDC03),
pp. 13921397, Maui, Hawaii, 2003
C[11] D. Di Martino, A. Germani, C. Manes, P. Palumbo, ''Polynomial approach for filtering and identification of a class of uncertain systems'', 2nd IFAC Symposium on System, Structure and Control (SSSC04), pp. 579584, Oaxaca, Mexico, 2004 C[12] A. Germani, C. Manes, P. Palumbo, ''Polynomial filtering for stochastic nonGaussian descriptor systems'', 43rd Conference on Decision and Control (CDC04), pp. 20882093, Paradise Island, The Bahamas, 2004 C[13] D. Di Martino, A. Germani, C. Manes, P. Palumbo, ''Quadratic filtering for simultaneous state and parameter estimation of uncertain systems'', 43rd Conference on Decision and Control (CDC04), pp. 35693574, Paradise Island, The Bahamas, 2004 C[14] D. Di Martino, A. Germani, C. Manes, P. Palumbo, "State observation for linear systems with polynomial w.r.t. state output", 43rd Conference on Decision and Control (CDC04), pp. 38863891, Paradise Island, The Bahamas, 2004 C[15] A. Germani, C. Manes, P. Palumbo, ''A family of polynomial filters for discretetime nonlinear stochastic systems'', 16th IFAC World Congress on Automatic Control (IFAC2005), Prague, Czech Republic, 2005 C[16] A. De Gaetano, D. Di Martino, A. Germani, C. Manes, P. Palumbo, ''Distributeddelays models of the glucoseinsulin homeostasis and asymptotic state observation'', 16th IFAC World Congress on Automatic Control (IFAC2005), Prague, Czech Republic, 2005 C[17] P. Palumbo, W.H. OngClausen, S. Panunzi, A. De Gaetano, "Analysis of an impulsive model of subcutaneously delivered insulin kinetics'', 7th Hellenic European Conference on Computer Mathematics and its Applications (HERCMA2005), Athens, Greek, 2005 C[18] A. Germani, C. Manes, P. Palumbo, ''Polynomial filtering and indentification of discretetime nonlinear uncertain stochastic systems'', 44th Conference on Decision and Control & European Control Conference (CDCECC05), pp. 19171922, Seville, Spain, 2005 C[19] A. Germani, C. Manes, P. Palumbo, ''Filtering of differential nonlinear systems via a Carleman approximation approach'', 44th Conference on Decision and Control & European Control Conference (CDCECC05), pp. 59175922, Seville, Spain, 2005 C[20] P. Palumbo, S. Panunzi, A. De Gaetano, ''Stability analysis of a discretedelay model of the glucoseinsulin system'', 6th IFAC Workshop on Time Delay Systems (TDS06), L'Aquila, Italy, 2006 C[21] P. Palumbo, A. De Gaetano, ''A closed loop optimal control of the plasma glycemia'', 45th IEEE Conference on Decision and Control (CDC06), pp. 679684, San Diego, California, 2006 C[22] D. Di Martino, A. Germani, C. Manes, P. Palumbo, ''Design of observers for systems with rational output function'', 45th IEEE Conference on Decision and Control (CDC06), pp. 16411646, San Diego, California, 2006 C[23] A. Germani, F. Graziosi, C. Manes, G. Ocera, P. Palumbo, ''Recursive filtering for logRice signals'', 45th IEEE Conference on Decision and Control (CDC06), pp. 31503155, San Diego, California, 2006 C[24] C. Manes, A. Martinelli, F. Martinelli, P. Palumbo, ''Mobile robot localization based on a polynomial approach'', International Conference on Robotics and Automation (ICRA07), Rome, Italy, pp. 35393544, 2007 C[25] G. Mavelli, P. Palumbo, ''A
Carleman approximation scheme for a stochastic optimal
nonlinear control problem'', 9th European Control
Conference (ECC07), Kos, Greece, pp. 36723678, 2007
C[26] A. Germani, C. Manes, P. Palumbo, ''State space representation of a class of MIMO systems via positive systems'', 46th Conference on Decision and Control (CDC07), New Orleans, Louisiana, pp. 476481, 2007 C[27] A. Germani, C. Manes, P. Palumbo, ''Simultaneous system identification and channel estimation: a hybrid system approach'', 46th Conference on Decision and Control (CDC07), New Orleans, Louisiana, pp. 17641769, 2007 C[28] G. Mavelli, P. Palumbo, ''A Carleman approximation scheme for a stochastic optimal control problem in the continuoustime framework'', accepted for presentation at 17th IFAC World Congress on Automatic Control (IFAC2008), Seoul, South Korea, July 2008 C[29] F. Carravetta, G. Felici, P. Palumbo, ''Regulation of a manned seasurface vehicle via stochastic optimal control'', accepted for presentation at 17th IFAC World Congress on Automatic Control (IFAC2008), Seoul, South Korea, July 2008 C[30] P. Palumbo, P. Pierdomenico, S. Panunzi, A. De Gaetano, ''Robust closedloop control of plasma glycemia: a discretedelay model approach'', 47th Conference on Decision and Control (CDC08), Cancun, Messico, pp. 33303335, 2008 C[31] F. Carravetta, G. Felici, P. Palumbo, ''Frequency based model validation and parameter identification of a sea surface vehicle'', 14th IEEE International Conference on Methods and Models in Automation and Robotics (MMAR2009), Miedzyzdroje, Poland, 2009 C[32] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''Observerbased closedloop control of plasma glycemia'', 48th Conference on Decision and Control (CDC09), pp.61896194, Shanghai, China, December 2009 C[33] F. Cacace, A. Germani, P. Palumbo, ''Observerbased identification of a multioutput feedforward loop from gene expression data'', 48th Conference on Decision and Control (CDC09), pp.35073512, Shanghai, China, December 2009 C[34] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''Digital closedloop control of plasma glycemia'', 49th Conference on Decision and Control (CDC10), pp.833838, Atlanta, Georgia, 2010 C[35] F. Carravetta, P. Palumbo, P. Pepe, ''Quadratic optimal control of linear systems with timevarying input delay'', 49th Conference on Decision and Control (CDC10), pp.49965000, Atlanta, Georgia, 2010 C[36] F. Cacace, L. Farina, A. Germani, P. Palumbo, ''Discretetime models for gene transcriptional regulation networks'', 49th Conference on Decision and Control (CDC10), pp.76187623, Atlanta, Georgia, 2010 C[37] F. Muzi, A. De Sanctis, P. Palumbo, ''Distance protection for smart grids with massive generation from renewable sources'', 6th IASME/WSEAS Conference on Energy & Environment (EE11), pp.208213, Cambridge, UK, 2011 C[38] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''Glucose control by subcutaneous insulin administration: a DDE modelling approach'', 18th IFAC World Congress on Automatic Control (IFAC2011), pp.14711476, Milan, Italy, 2011 C[39] F. Cacace, A. Germani, P. Palumbo, ''A new approach to nonlinear filtering via a mixed state observer and polynomial KalmanBucy scheme'', accepted for presentation at the 18th IFAC World Congress on Automatic Control (IFAC2011), pp.44774482, Milan, Italy, 2011 C[39] F. Cacace, A. Germani, P. Palumbo, ''A new approach to nonlinear filtering via a mixed state observer and polynomial KalmanBucy scheme'', 18th IFAC World Congress on Automatic Control (IFAC2011), pp.44774482, Milano, Italia, 2011 C[40] F. Cacace, A. Germani, P. Palumbo, ''A state observer approach to filter stochastic nonlinear differential systems'', 50th Conference on Decision and Control and European Control Conference (CDC11), pp.79177922, Orlando, Florida, 2011 C[41] P. Palumbo, G. Pizzichelli, S. Panunzi, P. Pepe, A. De Gaetano, ''Tests on a virtual patient for an observerbased, closedloop control of plasma glycemia'', 50th Conference on Decision and Control and European Control Conference (CDC11), pp.69366941, Orlando, Florida, 2011 C[42] F. Carravetta, P. Palumbo, P. Pepe, ''Memoryless solution to the infinite horizon optimal control of linear timeinvariant systems with delayed input'', 31st IASTE Asian Conference on Modeling, Identification and Control (AsiaMIC2012), 6 pages, Phucket, Thailand, 2012 C[43] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''Observerbased glucose control via subcutaneous insulin administration'', 8th IFAC Symposium on Biological and Medical Systems (BMS12), 6 pages, Budapest, Hungary, 2011 C[44] K. Juagwon, Y. Lenbury, A. De Gaetano, P. Palumbo, "Reconstruction of insulin secretion under the effects of hepatic extraction during OGTT: a modelling and convolution approach", 13rd WSEAS American Conference on Applied Mathematics (AMERICANMATH'13), pp.8590, Cambridge, Massachussets, 2013 C[45] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''Observerbased closedloop control for the glucoseinsulin system: local InputtoState Stability with respect to unknown meal disturbances'', American Control Conference (ACC13), pp.17511756, Washington, DC, 2013 C[46] A. Borri, F. Carravetta, G. Mavelli, P. Palumbo, ''Some Results on the structural properties and the solution of the Chemical Master Equation'', American Control Conference (ACC13), pp.37713776, Washington, DC, 2013 C[47] A. Borri, F. Carravetta, G. Mavelli, P. Palumbo, ''Chemical Master Equations: a mathematical scheme for the multisite phosphorylation case'', 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH13), pp.681688, Reykjavik, Island, 2013 C[48] P. Palumbo, P. Pepe, J.D. Kong, S.S. Kumar, S. Panunzi, A. De Gaetano, ''Regulation of the human plasma glycemia by means of glucose measurements and subcutaneous insulin administration'', 3rd IFAC International Conference on Intelligent Control and Automation Science (ICONS13), pp.96101, Chengdu, China, 2013 C[49] F. Cacace, V. Cusimano, A. Germani, P. Palumbo, ''The Observer Follower Filter for stochastic differential systems with sampled measurements'', 52nd IEEE Conference on Decision and Control (CDC13), pp.2530, Florence, Italy, 2013 C[50] A. De Gaetano, C. Gaz, C. Gori Giorgi, P. Palumbo, ''An islet population model of pancreatic insulin production'', 52nd IEEE Conference on Decision and Control (CDC13), pp.33553360, Florence, Italy, 2013 C[51] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''Closedloop glucose control: application to the Euglycemic Hyperinsulinemic Clamp'', 52nd IEEE Conference on Decision and Control (CDC13), pp.44614466, Florence, Italy, 2013 C[52] P. Palumbo, G. Pizzichelli, S. Panunzi, P. Pepe, A. De Gaetano, ''Closedloop control scheme for the euglycemic hyperinsulinemic clamp: validation on virtual patients'', 19th IFAC World Congress (IFAC2014), pp.20882093, Cape Town, South Africa, 2014 C[53] F. Cacace, V. Cusimano, A. Germani, P. Palumbo, ''A Carleman discretization approach to filter nonlinear stochastic systems with sampled measurements'', 19th IFAC World Congress (IFAC2014), pp.95349539, Cape Town, South Africa, 2014 C[54] F. Carravetta, C. Manes, P. Palumbo, ''Filtering and parameter estimation for a class of Hidden Markov Models with application to bubblecounting in microfluidics'', 19th IFAC World Congress (IFAC2014), pp.95409544, Cape Town, South Africa, 2014 C[55] S. Panunzi, A. Borri, P. Palumbo, L. Kovacs, A. De Gaetano, ''Simulation of insulin regimen and glucose profiles in Type 1 Diabetic Patient'', IEEE International Conference on Systems, Man, and Cybernetics (SMC2014), pp.24642469, San Diego, California, 2014 C[56] A. Bersani, A. Borri, F. Carravetta, G. Mavelli, P. Palumbo, ''QuasiSteadyState Approximations of the Chemical Master Equation in enzyme kinetics  application to the double phosphorylation/dephosphorylation cycle'', 53rd IEEE Conference on Decision and Control (CDC14), pp.30533058, Los Angeles, California, 2014 C[57] P. Latafat, P. Palumbo, P. Pepe, L. Kovacs, S. Panunzi, A. De Gaetano, ''An LMIbased controller for the glucoseinsulin system'', 14th European Control Conference (ECC2015), pp.712, Linz, Austria, 2015 C[58] A. Borri, P. Palumbo, A. Singh, ''Metabolic noise reduction for enzymatic reactions: the role of a negative feedback'', 54th IEEE Conference on Decision and Control (CDC15), pp. 25372542, Osaka, Japan, 2015 C[59] V. Cusimano, P. Palumbo, F. Papa, ''Closedloop control of tumor growth by means of antiangiogenic administration'', 54th IEEE Conference on Decision and Control (CDC15), pp.77897794, Osaka, Japan, 2015 C[60] A. Borri, S. Panunzi, P. Palumbo, C. Manes, A. De Gaetano, ''Glucose control with incomplete information'', IEEE International Conference on Systems, Man, and Cybernetics (SMC2016), pp.17801784, Budapest, Hungary, 2016 C[61] F. Cacace, V. Cusimano, A. Germani, P. Palumbo, ''Carleman discretization of impulsive systems: applications to the optimal control problem of antiangiogenic tumor therapies'', 55th IEEE Conference on Decision and Control (CDC16), pp.10421047, Las Vegas, Nevada, 2016 C[62] A. Borri, F. Carravetta, P. Palumbo, ''Cubification of nonlinear stochastic differential equations and approximate moments calculation of the Langevin equation'', 55th IEEE Conference on Decision and Control (CDC16), pp.45404545, Las Vegas, Nevada, 2016 C[63] A. Borri, P. Palumbo, A. Singh, ''Noise reduction for enzymatic reactions: a case study for stochastic product clearance'', 55th IEEE Conference on Decision and Control (CDC16), pp.58515856, Las Vegas, Nevada, 2016 C[64] P. Pepe, P. Palumbo, S. Panunzi, A. De Gaetano, ''Local sampleddata control for the glucose insulin system'', American Control Conference Conference (ACC17), pp.110115, Seattle, Washington, 2017 C[65] J.G. Pires, A. Borri, A. De Gaetano, C. Manes, P. Palumbo, ''A shortterm dynamical model for ghrelin'', 20th IFAC World Congress (IFAC17), pp.1150311508, Toulouse, France, 2017 C[66] C. Gaz, A. De Gaetano, C. Manes, P. Palumbo, A. Borri, S. Panunzi, ''Effective control of glycemia using a simple discretedelay model'', 20th IFAC World Congress (IFAC17), pp.1406814073, Toulouse, France, 2017 C[67] M. Di Ferdinando, P. Pepe, P. Palumbo, S. Panunzi, A. De Gaetano, ''Robust global nonlinear sampleddata regulator for the glucoseinsulin system'', 56th IEEE Conference on Decision and Control (CDC17), pp. 46864691, Melbourne, Australia, 2017 C[68] F. Cacace, V. Cusimano, A. Germani, P. Palumbo, M. Papi, ''Optimal linear filter for a class of nonlinear stochastic differential systems with discrete measurements'', 56th IEEE Conference on Decision and Control (CDC17), pp. 28072812, Melbourne, Australia, 2017 C[69] A. Borri, P. Palumbo, A. Singh, ''Noise propagation in a class of metabolic networks'', 56th IEEE Conference on Decision and Control (CDC17), pp. 447452, Melbourne, Australia, 2017 C[70] P. Palumbo, M. Ghasemi, M. Fakhroleslam, ''On enzymatic reactions: the role of a feedback from the substrate'', 56th IEEE Conference on Decision and Control (CDC17), pp. 441446, Melbourne, Australia, 2017 C[71] A. Borri, P. Palumbo, A. Singh, ''Noise propagation in feedback coupling between cell growth and metabolic activity'', accepted for presentation at 57th IEEE Conference on Decision and Control (CDC18), Miami Beach, Florida, Dec 2018 TECHNICAL RESEARCH REPORTS Rc[1] C. Manes, P. Palumbo, P. Pepe, ''Analysis of an approximation scheme for the LQG control of flexible structures'', Department of Electrical Engineering, Research Report, No. 9827, L'Aquila, 1998 Rc[2] A. Germani, C. Manes, P. Palumbo, ''Polynomial filtering for stochastic nonGaussian descriptor systems'', IASICNR Research Report, No. 526, Rome, 2000 Rc[3] A. Germani, C. Manes, P. Palumbo, ''Optimal linear filtering for bilinear stochastic differential systems with unknown inputs'', IASICNR Research Report, No. 541, Rome, 2000 Rc[4] A. Germani, C. Manes, P. Palumbo, ''Kalman Bucy filtering for singular stochastic differential systems'', IASICNR Research Report, No. 545, Rome, 2001 Rc[5] A. Germani, C. Manes, P. Palumbo, ''State estimation for a class of stochastic variable structure systems'', IASICNR Research Report, No. 548, Rome, 2001 Rc[6] A. Germani, C. Manes, P. Palumbo, ''Filtering of switching systems via a singular minimax approach'', IASICNR Research Report, No. 552, Rome, 2001 Rc[7] A. Germani, C. Manes, P. Palumbo, ''Polynomial filtering for stochastic systems with Markovian switching coefficients'', IASICNR Research Report, No. 570, Rome, 2002 Rc[8] A. Germani, C. Manes, P. Palumbo, ''Polynomial extended Kalman filtering for discretetime nonlinear stochastic systems'', IASICNR Research Report, No. 572, Rome, 2002 Rc[9] A. Germani, C. Manes, P. Palumbo, ''A minimum variance filter for discretetime linear systems perturbed by unknown nonlinearities'', IASICNR Research Report, No. 575, Rome, 2002 Rc[10] A. Germani, C. Manes, P. Palumbo, M. Sciandrone, ''A Newtonlike higher order method for the solution of nonlinear equations'', IASICNR Research Report, No. 585, Rome, 2003 Rc[11] D. Di Martino, A. Germani, C. Manes, P. Palumbo, ''Quadratic filtering for simultaneous state and parameter estimation of uncertain systems'', IASICNR Research Report, No. 589, Rome, 2003 Rc[12] D. Di Martino, A. Germani, C. Manes, P. Palumbo, ''State observation for linear systems with linear state dynamics and polynomial output'', IASICNR Research Report, No. 595, Rome, 2003 Rc[13] D. Di Martino, A. Germani, C. Manes, P. Palumbo, ''A polynomial approach for simultaneous channel estimation and data detection'', IASICNR Research Report, No. 599, Rome, 2003 Rc[14] D. Di Martino, A. Germani, C. Manes, P. Palumbo, ''Polynomial approach for filtering and identification of a class of uncertain systems'', IASICNR Research Report, No. 603, Rome, 2003 Rc[15] A. Germani, C. Manes, P. Palumbo, '' A family of polynomial filters for discretetime nonlinear stochastic systems '', IASICNR Research Report, No. 610, Rome, 2004 Rc[16] A. De Gaetano, D. Di Martino, A. Germani, C. Manes, P. Palumbo, ''Distributeddelay models of the glucoseinsulin homeostasis and asymptotic state observation'', IASICNR Research Report, No. 618, Rome, 2004 Rc[17] P. Palumbo, S. Panunzi, A. De Gaetano, ''Qualitative properties of solutions for two delaydifferential models of the glucoseinsulin system'', IASICNR Research Report, No. 620, Rome, 2004 Rc[18] S. Panunzi, P. Palumbo, A. De Gaetano, ''Modeling IVGTT data with delay differential equations'', IASICNR Research Report, No. 625, Rome, 2004 Rc[19] C. Manes, A. Martinelli, F. Martinelli, P. Palumbo, ''Mobile robot localization based on a polynomial approach'', IASICNR Research Report, No.635, Rome, 2006 Rc[20] G. Mavelli, P. Palumbo, ''A Carleman approximation scheme for a stochastic optimal control problem in the continuoustime framework'', IASICNR Research Report, No.644, Rome, 2006 Rc[21] P. Palumbo, W.H. OngClausen, S. Panunzi, A. De Gaetano, "Analysis of an impulsive model of subcutaneously delivered insulin kinetics'', IASICNR Research Report, No.647, Rome, 2006 Rc[22] A. Germani, F. Graziosi, C. Manes, G. Ocera, P. Palumbo, ''Recursive filtering for logRice signals'', IASICNR Research Report, No.649, Rome, 2006 Rc[23] P. Palumbo, A. De Gaetano, ''A closed loop optimal control of the plasma glycemia'', IASICNR Research Report, No.652, Rome, 2006 Rc[24] A. Germani, C. Manes, P. Palumbo, ''Polynomial filtering and indentification of discretetime nonlinear uncertain stochastic systems'', IASICNR Research Report, No.655, Rome, 2006 Rc[25] L. Farina, A. Germani, G. Mavelli, P. Palumbo, ''Identification of regulatory network motifs from gene expression data'', IASICNR Research Report, No.667, Rome, 2007 Rc[26] F. Carravetta, G. Felici, P. Palumbo, ''Regulation of a manned seasurface vehicle via stochastic optimal control'', IASICNR Research Report, 0911, Rome, 2009 Rc[27] F. Carravetta, G. Felici, P. Palumbo, ''Frequencybased model validation and parameter estimation of a seasurface vehicle'', IASICNR Research Report, 0912, Rome, 2009 Rc[28] A. Germani, C. Manes, P. Palumbo, ''State and mode estimation of stochastic systems with switching measurements'', IASICNR Research Report, 0913, Rome, 2009 Rc[29] P. Palumbo, G. Mavelli, L. Farina, L. Alberghina, ''Networks and circuits in cell regulation'', IASICNR Research Report, 201005, Rome, 2010 Rc[30] F. Carravetta, P. Palumbo, P. Pepe, ''Quadratic optimal control of linear systems with timevarying input delay'', IASICNR Research Report, 201009, Rome, 2010 Rc[31] A. De Gaetano, A. Matone, P. Palumbo, A.M. Agnes, F. Ria, S. Magalini, ''Modeling rejection immunity'', IASICNR Research Report, 201010, Rome, 2010 Rc[32] P. Palumbo, S. Ditlevsen, A. Bertuzzi, A. De Gaetano, ''Mathematical modeling of the glucoseinsulin system: a Review paper'', IASICNR Research Report, 201109, Rome, 2011 Rc[33] F. Cacace, A. Germani, P. Palumbo, ''The Observer Follower Filter'', IASICNR Research Report, 201206, Rome, 2012 Rc[34] A. Borri, F. Carravetta, G. Mavelli, P. Palumbo, ''A study on the structural properties and the solution of the chemical master equation'', IASICNR Research Report, 201210, Rome, 2012 Rc[35] P. Palumbo, P. Pepe, S. Panunzi, A. De Gaetano, ''A study on observerbased glucose control by means of intravenous insulin administration'', IASICNR Research Report, 201211, Rome, 2012 Rc[36] J. Li, M. Wang, A. De Gaetano, P. Palumbo, S. Panunzi, ''Some results on the global stability of the equilibrium for an IVGTT model'', IASICNR Research Report, 201212, Rome, 2012 Rc[37] F. Cacace, A. Germani, P. Palumbo, ''A study on observerbased algorithms to infer information from gene expression data", IASICNR Research Report, 201213, Rome, 2012 Rc[38] A. Borri, F. Carravetta, P. Palumbo, ''A cubification approach for the approximate moments computation in stochastic differential equations: application to the Chemical Langevin Equation'', IASICNR Research Report, 201601, Rome, 2016 Rc[39] A. Borri, S. Panunzi, C. Manes, P. Palumbo, A. De Gaetano, ''Preliminary results on glucose control wityh sampled information'', IASICNR Research Report, 201602, Rome, 2016 The order of the authors is alphabetical in all the publications, except for R[5, 8, 9, 1113, 15, 16, 2025, 28, 29, 31, 32, 35, 38, 40], Ra[1, 2, 4], B[15], C[17, 20, 21, 30, 32, 34, 37, 38, 41, 4345, 48, 51, 52, 55, 57, 60, 6467, 70], Rc[17, 18, 21, 23, 29, 31, 32, 35, 36, 39] NATIONAL AND INTERNATIONAL CONFERENCES ATTENDED


Aprile 6, 2009
