Archives

The global adoption of artificial intelligence (AI) has increased dramatically in recent years, becoming commonplace in manyfields. Such a pervasiveness has led to changes in how AI is perceived, strengthening discussions on its societal consequences.Thus, a new class of requirements for AI-based solutions emerged. Broadly speaking, those on “explainability” aim to providea transparent representation of […]

The global adoption of artificial intelligence (AI) has increased dramatically in recent years, becoming commonplace in manyfields. Such a pervasiveness has led to changes in how AI is perceived, strengthening discussions on its societal consequences.Thus, a new class of requirements for AI-based solutions emerged. Broadly speaking, those on “explainability” aim to providea transparent representation of […]

SUMOylation is a crucial post-translational modification that regulates protein function at multiple levels. In this review the authors discuss the SUMOylation impact in the regulation of the synapse compartment and the therapeutic potential of modulating SUMOylation in Alzheimer’s disease as example of neurodegenerative disorders. SUMOylation balance: a key determinant in synapse physiology. Frontiers in Physiology […]