SUMOylation balance: a key determinant in synapse physiology.

• Post by: stefano_lusetti
• 1 Ottobre 2025
• No Comment

SUMOylation is a crucial post-translational modification that regulates protein function at multiple levels. In this review the authors discuss the SUMOylation impact in the regulation of the synapse compartment and the therapeutic potential of modulating SUMOylation in Alzheimer’s disease as example of neurodegenerative disorders.

SUMOylation balance: a key determinant in synapse physiology. Frontiers in Physiology 2025 Alessia Bertozzi, Walter Toscanelli, Giuditta Castellitto, Claudio Grassi and Claudia Colussi; 10.3389/fphys.2025.1675598

Data di pubblicazione: 1 Ottobre 2025
Link esterno: https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1675598/full