Address

Fond .Santa Lucia
Stanza: Lab 111

Contact Information

Call: Lab 111

Email: cinzia.volonte@cnr.it, c.volonte@hsantalucia.it

Personal site: www.iasi.cnr.it

Cinzia Volonté

Role: Research Director

Research group: BIOSYS

As a neuroscientist, I am studying the features and mechanisms of neurodegeneration and neuroinflammation evoked during central nervous system diseases such as amyotrophic lateral sclerosis and multiple sclerosis. By performing preclinical pharmacological analysis in primary ex vivo cultures and in vitro cell lines, moreover in Drosophila and mice models, my key goal is to develop new effective therapeutic strategies against these devastating diseases.
Settori ERC:
LS1: Molecular and Structural Biology and Biochemistry,
LS5: Neurosciences and neural disorders.

Recent publications

  1. 2023
    Machine learning as a new tool in neurological disease prevention, diagnosis and treatment
  2. 2023
    Amyotrophic lateral sclerosis disease burden: doing better at getting better
    Cinzia Volonté, S Amadio
  3. 2023
    A step in the ALS direction: lessons from the purinome.
    Cinzia Volonté, JJ Yerbury, R Sluyter
  4. 2022
    Vitamin B6 rescues insulin resistance and glucose-induced DNA damage caused by reduced activity of Drosophila PI3K
    Mascolo E, Liguori F, Merigliano C, Schiano L, Gnocchini E, Pilesi E, Cinzia Volonté, Di Salvo ML, Contestabile R, Tramonti A, Vernì F
  5. 2022
    The Histamine and Multiple Sclerosis Alliance: Pleiotropic Actions and Functional Validation
  6. 2022
    Repurposing of Trimetazidine for Amyotrophic Lateral Sclerosis: a study in SOD1 G93A mice
    Silvia Scaricamazza, Illari Salvatori, Susanna Amadio, Valentina Nesci, Alessio Torcinaro, Giacomo Giacovazzo, Aniello Primiano, Michela Gloriani, Niccolò Candelise, Luisa Pieroni, Jean-Philippe Loeffler, Frederique Renè, Cyril Quessada, Tesfaye W Tefera, Hao Wang, Frederik J Steyn, Shyuan T Ngo, Gabriella Dobrowolny, Elisa Lepore, Andrea Urbani, Antonio Musarò, Cinzia Volonté, Elisabetta Ferraro, Roberto Coccurello, Cristiana Valle, Alberto Ferri
  7. 2022
    A deep scream into the future
    Cinzia Volonté, S Amadio
  8. 2022
    Delineating purinergic signaling in Drosophila
    Cinzia Volonté, F Alberti, G Vitale, F Liguori
  9. 2022
    Rethinking purinergic concepts and updating the emerging role of P2X7 and P2X4 in amyotrophic lateral sclerosis
    Cinzia Volonté, S Amadio
  10. 2022
    Repurposing Histaminergic Drugs in Multiple Sclerosis

Current projects

  1. FATALSDRUG
    Progetti@CNR - FATALSDRUG - IASI
    Research group: BIOSYS
    Url progetto: https://www.cnr.it/it/progetti-di-ricerca-cnr
    Start date: 01/01/2020
    End date: 14/02/2025