Dr. Francesco Liguori obtained a PhD in Life Sciences by discussing a thesis on the role of transposable elements in the pathogenesis of Huntington’s Disease, using the fruit fly Drosophila melanogaster as model organism. Currently, in the Cellular Neurobiology Unit at Santa Lucia Foundation IRCCS, he is characterizing new pathways of neuroinflammation and neurodegeneration in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS), leveraging the manifold potentialities of Drosophila to dissect the genetic and molecular aspects of neurodegenerative diseases. The ultimate aim of his research is the identification of potential therapeutic targets to improve the degenerative and inflammatory phenotypes of ALS.
Settori ERC:
LS2_1 Molecular genetics, reverse genetics, forward genetics, genome editing,
LS5_7 Neurological disorders.